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Chronic Neutrophilic Leukaemia

Chronic neutrophilic leukaemia is another rare myeloproliferative neoplasm in which too many neutrophils are made in the bone marrow. These cells spill out into the circulating blood and tend to accumulate in the liver and spleen, which become enlarged as a result.

Chronic neutrophilic leukaemia is usually a slowly progressing disease, closely related to another type of leukaemia called chronic myeloid leukaemia. Its natural course can vary considerably between individuals with survival times ranging from 6 months to over 20 years. Treatment options may include the use of chemotherapy drugs such as busulphan or hydroxyurea, which are given in tablet or capsule form. These drugs are used to control the high white cell count.